Converging on cancer at the nanoscale
Marking its first anniversary, the Koch Institute’s Marble Center for Cancer Nanomedicine goes full steam ahead. See the article in MIT News here.
MIT’s Koch Institute for Integrative Cancer Research held on June 16th its Annual Cancer Research Symposium: Convergence of Science and Engineering in Cancer. Convergence—the merging of historically distinct disciplines such as engineering, physics, computer science, chemistry, mathematics, and the life sciences—has created extraordinary opportunities in cancer research and care. Leaders in this emerging field discussed innovative new approaches and technologies to better detect, monitor, treat, and prevent cancer. See the article from the Boston Globe here and the KI press release here.
Drs. Belcher, Bhatia, and Hammond are innovating at the tiniest scale—developing tools to see, target and kill cancer cells before they can cause any harm. See article here.
New technology can detect tiny ovarian tumors
Synthetic biomarkers could be used to diagnose ovarian cancer months earlier than now possible. See article here. Photo credit: Nephron/CC BY-SA 3.0.
Tiny Trojan Horses: Tumor-penetrating nanoparticles infiltrate cancer cells
Winner of the 2017 Koch Institute Public Galleries (click here to see other winners). This image shows biocompatible nanoparticles (yellow) inside clusters of pancreatic cancer cells (pink). The particles’ two-peptide uptake system—one to target the tumor, the second to penetrate it—was specially designed to overcome known difficulties in treating pancreatic cancer. Funded in part by the Marble Center for Cancer Nanomedicine at MIT's Koch Institute. Photo credit: Liangliang Hao, Srivatsan Raghavan, Emilia Pulver, Jeffrey Wyckoff, Sangeeta Bhatia.
Tethered nanoparticles make tumor cells more vulnerable
New strategy could improve performance of some immune-based drugs. See article here. Photo credit: Second Bay Studios.
Robert Langer, The Delivery Man
The downfall of many drugs is that they are not taken regularly or as prescribed. Robert Langer has developed a polymer that could solve this problem. See article here. Photo credit: Nick D Burton; original article by Kathryn Nave from WIRED Magazine.
Image gallery for National Nanotechnology Day
In honor of the first annual National Nanotechnology Day, the Koch Institute for Integrative Cancer Research at MIT presents an interactive peek into how researchers across the MIT campus are using nanomaterials to explore and improve the world. Source: The Koch Institute for Integrative Cancer Research at MIT.
A Golden Opportunity for Drug Delivery
This image explores how exotic materials can be used to deliver drugs on-demand using light-triggered devices fabricated from integrated polymer nanotechnologies. Source: Erik Dreaden of the Hammond Laboratory at the Koch Institute for Integrative Cancer Research at MIT.
Suit Your Cell: Designing Custom Biomaterials
This image shows sixteen polymer spots from an automated screening experiment. Source: Asha K. Patel of the Anderson Laboratory at the Koch Institute for Integrative Cancer Research at MIT.
Target Practice: Improving Gene Therapy with Nanotechnology
This image shows nanoparticles delivering siRNA to the cytoplasm of cervical tumor cells. Source: Omar Khan and Edmond Zaia of the Langer and Anderson Laboratories at the Koch Institute for Integrative Cancer Research at MIT.
Therapeutic Cells Loaded with Synthetic Nanoparticles
Source: Matthias T. Stephan, James J. Moon, Soong Ho Um, Anna Bershteyn and Darrell J. Irvine of the Irvine Laboratory at the Koch Institute for Integrative Cancer Research at MIT.
Virus-Templated Copper Nanowires with Fused Silver Nanoparticles
Source: John Burpo and Angela M. Belcher of the Biomolecular Materials Laboratory at the Koch Institute for Integrative Cancer Research at MIT.
Blood, Heat, and Tumors: Improving Drug Delivery with Gold Nanorods
This image, submitted by Alex Bagley, shows gold nanorods in a living tumor. Source: Alex Bagley from the Laboratory for Multiscale Regenerative Technologies at the Koch Institute for Integrative Cancer Research at MIT.
The Marble Center for Cancer Nanomedicine aims to galvanize the MIT research community in efforts to have an indelible impact on cancer diagnosis and care.